Which organ may be severely damaged by HBV (Hepatitis B)?

The liver is the organ that is most severely damaged by Hepatitis B virus (HBV). This virus primarily attacks liver cells, leading to inflammation and potentially resulting in chronic conditions such as cirrhosis, liver failure, or even liver cancer over time. The liver's role in filtering toxins, producing essential proteins, and managing metabolism means that damage from HBV can have systemic effects on overall health.

Other organs listed, like the heart, lung, and kidney, do not have the same direct correlation with the impact of HBV infection. While HBV can complicate existing conditions or overall health, it is the liver that is fundamentally most at risk and directly affected by the viral infection, making it critical to understand the significance of Hepatitis B in terms of liver health and disease.